Acetic acid was collected from laboratory of Bangladesh University. CurrOpinClinNutrMetab Care. Reviews of P. pellucida document in vitro and animal data on the anti-inflammatory, chemotherapeutic, and analgesic properties found in the crude extracts. Our result showed that supplementation of diabetic mice with plant extracts resulted in significant elevation in hepatic glycogen content. FIG. Hasib Sheikh*, Shotabdi Sikder , Sagar Kumar Paul , A.M. Rashedul Hasan , Md. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. FIG. Geographical Distributions. Scientific Name(s): Peperomia pellucida L. HBK. Bangladesh, Asiatic Society of Bangladesh, 1998, pp 77-78. 2: HYPOGLYCEMIC EFFECT OF THE ETHANOLIC EXTRACT OF PEPEROMIA PELLUCIDA (LEAF AND STEM) ON DIABETIC MICE. Exercise training-induced lowering of inflammatory (CD14+CD16+) monocytes: a role in the anti-inflammatory influence of exercise? In salads, the fresh plant has the crispness of carrot sticks and celery. Percentage of inhibition was 58.16 with the number of writhing 11.8±SEM in 300mg/kg inhibition was observed with 6.8 ±SEM writhing. Am J Physiol. Common Name(s): Coracaozinho, Erva-de-jaboti, Erva-de-jabuti, Erva-de-vidro, Lingua de sapo, Shiny bush, Silver bush Medically reviewed by Drugs.com. Clinical Overview Use. Peperomia pellucida is also used in traditional Ayurvedic medicine 6. J Am Geriatr Soc. The aerial parts of Peperomia pellucidaand Cyperus esculentuswere collected from Trikaripur forest area, kasaragod district of Kerala, India, dried and extracted with ethanol (70%). With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age. How Peperomia Pellucida is effective for various diseases is listed in repertory format. Ghani A. Uses, Benefits, Cures, Side Effects, Nutrients in Peperomia Pellucida. The fractions were more active than the crude extracts.Muñoz 2000 Other studies document similar results for activity against numerous species, including Bacillus subtilis, Escherichia coli, Pseudomonas aeruginosa, and Staphylococcus aureus.Bojo 1994, Lee 2016, Chloroform extracts from dried leaves of P. pellucida, particularly apiol and pachypophyllin, have antifungal activity against Trichophyton mentagrophytes.Ragasa 1998, A whole plant extract inhibited growth of the chloroquine-resistant Plasmodium falciparum Indo strain by 95% in vitro at 100 mg/mL, and the rodent malaria Plasmodium vinckei petteri by 78% in vivo at 1,000 mg/kg. Last updated on Mar 20, 2020. P. pellucida L. HBK is a herbaceous plant found in many South American and Asian countries. 3) compared to control group. The present investigation established the pharmacological evidence to support the folklore claim and that of the plant has antidiabetic, analgesic and anti-inflammatory activity. is a wild plant that can be found in various shaded and damp habitats in tropical and subtropical climate. Epub 2007 May 15. Review. In addition, the plant extract of Peperomia pellucida gave positive reactions for rdiac glycosides from slightly present to … Peperomia pellucida extracts contain the presence of flavonoids and related phenolic compounds. List of various diseases cured by Peperomia Pellucida. http://www.flowersofindia.in/catalog/ slides/Shiny%20Bush.html. 2013; 4(1); 458-463. The species develops during rainy periods (often in the spring) and thrives in loose, humid soils under the shade of trees. TABLE 2: HYPOGLYCEMIC EFFECT OF THE ETHYL ACETATE EXTRACT OF PEPEROMIA PELLUCIDA (LEAF AND STEM) ON DIABETIC MICE, FIG. Decreased activities of the enzymes involved in glucose homeostasis in liver and kidney such as hexokinase has been reported in diabetic animal resulting in depletion of liver and muscle glycogen content 32. com/plants/2180.htm] . It has been used in salads or as a cooked vegetable to help relieve rheumatic joint pain.Aziba 2001, Khan 2002, Other medicinal properties vary depending on region. J Ethnopharmacol. The plant species interferes with prostaglandin synthesis. Information regarding pregnancy and lactation is lacking. Timmerman KL, Flynn MG, Coen PM, Markofski MM, Pence BD. P. pellucida has significant anti-inflammatory effect after 4 hr with 3.47± SEM. Alloxan monohydrate was purchased from Loba chemie, India.Carrageenan was purchased from Otta chemika, India. It can be used to diagnose prediabetes and diabetes. It is found in various shaded, damp habitats all over Asia and the America, growing in clumps, thriving in loose, humid soils, tropical and subtropical climate. Group I animal received vehicle (1% Tween 80 in water), Group II received Diclofenac 10 mg/ kg body weight, Group III and Group IV were treated with 250 and 500mg/kg body weight (p.0.) Phytochemistry 2000; 55:779-782. Therefore the aim of this study was to evaluate the effects of the aqueous whole plant extract of Peperomia pellucida on fracture healing in female Wistar rats. These plants are used by the people of Indonesia as an external medicine for treating headaches during the fever, and the essence of betel water is used as a stomach medicine (Wijaya and Monica, 2004). Despite its wide range of folk medicinal uses in India sub-continent, there is very little scientific documentation available on its pharmacological and biological activities as well as its chemical constituents. So the observes analgesic activity may be attributed to these compound. Antifungal activity has been documented for arylpropanoids such as the apiols. 2010 Jun; 298(6): E1283-94. Finally, to find out the possible mechanism action of the plant extracts for their beneficial effect both in normal and alloxan-induced diabetic mice and the present study was designed to evaluate anti-inflammatory activity to the plant extracts of the Peperomia pellucida stem and leaf of the plants. Peperomia pellucida is an annual, shallow-rooted herb that belongs to the family Piperaceae (Ghani, 1998). The writhing count is positive of test group-I and test group-II (Fig. Bayma JD, Arruda MS, Müller AH, Arruda AC, Canto WC. Although indomethacin was more effective, greater anti-inflammatory action was documented with extracts from phenophase 1 and 2 during winter and spring, or vegetative and beginning-of-bloom stages, respectively. From the above table, (++) sign indicated larger amount of flavonoids and glycosides present in the study sample than others and tannins test was negative. This information is not specific medical advice and does not replace information you receive from your health care provider. Methods: A drill hole injury was created by inserting a drill bit inthe diaphysis of the femur. Am J PhysiolEndocrinolMetab. Eight Wistar rats received oral indomethacin 10 mg/kg as a control; another group of rats received P. pellucida aqueous extract 400 mg/kg for all 4 distinct phenophases 1 hour before subplantar injection of 1% carrageenan 0.1 mL/paw. 17, Authors: Sesquiterpenes appear to be the major chemical constituents in the essential oils. Chloroform extracts from dried leaves of P. pellucida have been shown to exhibit antifungal activity against Trichophyton menta- grophytes in vitro 20. 2006 Nov; 9(6):659-665. Review. This plant has externally used as a facial rinse for complexion problems. The oral administration of both doses of Peperomia pellucida extractsignificantly (p<0.001) inhibited writhing response induced by acetic acid in a dose dependent manner compared. Insulin is a potent inhibitor of lipolysis. Anti-inflammatory activity was evaluated by using the rat paw edema test induced by carrageenan. 6 bakteri. Chronic exercise training effects on immune function. (2017) Adhitia et al. Phytosterols such as … In 300mg/kg extract blood glucose level reduced from (20.53mM to 7.69 ±SEM) 62.64% was observed. Mice treated with extracts in Group-DPP (500mg/kg) showed a significant decrease in blood glucose concentration at 90min and 120min compared with diabetic control mice. The difference in results may be associated with use of different extracts, climatic conditions, and plant origin. In South America, A solution of the fresh juice of stem and leaves is used against eye inflammation 6. It is an herbaceous plant found in many South American and Asian countries. Lang CH, Frost RA, Bronson SK, Lynch CJ, Vary TC. Animals given P. pellucida aqueous extract 5 g/kg for 14 days showed no adverse reactions or changes in behavior or weight. No clinical data have been reported on human toxicity.de Fatima 2004. http://dx.doi.org/10.13040/IJPSR.0975-8232.4(1).458-63, All © 2020 are reserved by International Journal of Pharmaceutical Sciences and Research, This Journal licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported License, Subscribe to YouTube Channel of SPSR This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs.
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